Where/What/How we publish

Total number of publications: 101

Journals we published most in:

  • J. Chem. Inf. Model. - 17 publications.
  • J. Med. Chem. - 12 publications.
  • Eur. J. Med. Chem. - 5 publications.
  • Highest impact factor journals we have published in:

  • Nature Catalysis - Impact Factor (2019): 30.5
  • Accounts of Chemical Research - Impact Factor (2018): 21.7
  • Our most cited paper (below) has 574 citations (Google Scholar, Jan 2021)!

  • Moitessier N., Englebienne P., Lee D., Lawandi J., Corbeil C.R., Towards the development of universal, fast and highly accurate docking/scoring methods: A long way to go. British Journal of Pharmacology (2008), 153, SUPPL. 1, S7-S26
  • Clickhere to access all our publications!


    Shortlist of Highlighted Publications

    1. Stille, J.; Tjutrins, J.; Wang, G.; Venegas, F.A.; Hennecker, C.; Rueda, A.M.; Miron, C.E.; Pinus, S.; Labarre, A.; Plescia, J.; Burai Patrascu, M.; Vlaho, D.; Huot, M.; Mittermaier, A.K.; Moitessier, N.; Design, Synthesis and Biological Evaluation of Novel SARS-CoV-2 3CLpro Covalent Inhibitors. ChemRxiv - preprint, 2020 link

    2. Burai Patrascu, M., Pottel, J., Pinus, S., Bezanson, M., Norrby, P-O., Moitessier, N. From Desktop to Benchtop with Automated Computational Workflows for Computer Aided Design in Asymmetric Catalysis. Nature Catalysis 2020, 3, 574–584. link

    3. Plescia, J.; Moitessier, N. Design and discovery of boronic acid drugs. Eur. J. Med. Chem. 2020, 112270. link

    4. Plescia, J.; Dufresne, C.; Janmamode, N.; Wahba, A. S.; Mittermaier, A. K.; Moitessier, N. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur. J. Med. Chem. 2020, 185, 111783. link

    5. Plescia, J.; De Cesco, S.; Burai Patrascu, M.; Kurian, J.; Di Trani, J.; Dufresne, C.; Wahba, A. S.; Janmamode, N.; Mittermaier, A. K.; Moitessier, N. Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein Alpha. J. Med. Chem. 2019, 62, 7874-7884. link

    6. Champion C., Barigye, S., Wei W., Liu, Z., Labute, P., Moitessier, N. Atom Type Independent Modeling of the Conformational Energy of Benzylic, Allylic, and other Bonds Adjacent to Conjugated Systems. J. Chem. Inf. Model. 2019, 59, 4750-4763. link

    7. Luo J., Wei W., Waldisphul J., Moitessier, N. Challenges and current status of computational methods for docking small molecules to nucleic acids. Eur. J. Med. Chem. 2019, 168, 414-425. link

    8. Malek-Adamian E., Guenther D., Matsuda S., Martínez-Montero S., Zlatev I., Harp J., Burai Patrascu, M., Foster D. J., Fakhoury J. J., Perkins P., Moitessier N., Manoharan R., Taneja N., Bisbe A., Charisse K., Maier M. A., Rajeev K. G., Egli M., Manoharan M., Damha M. J. 4′-C-Methoxy-2′-Deoxy-2′-Fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J. Am. Chem. Soc. 2017, 139, 14542–14555. link

    9. Burai Patrascu, M., Malek-Adamian E., Damha M. J., Moitessier N. Accurately Modeling the Conformational Preferences of Nucleosides. J. Am. Chem. Soc. 2017, 139, 13620–13623. link

    10. Bezanson M., Tomberg, A., Moitessier N. Fluoride-mediated desulfonylative intramolecular cyclization to fused and bridged bicyclic compounds: A complex mechanism. J. Org. Chem. 2017, 82, 2579–2588. link

    11. Rocheleau, S., Pottel, J., Huskic, I., Moitessier N. Highly Regioselective Monoacylation of Unprotected Glucopyranoside using Transient Directing-Protecting Groups. Eur. J. Org. Chem. 2017, 646–656. link

    12. Mariaule G., De Cesco S., Airaghi F., Kurian J., Schiavini P., Rocheleau S., Huskić I., Auclair K., Mittermaier A., Moitessier N. 3-Oxo-hexahydro-1H-isoindole-4-carboxylic acid as a Drug Chiral Bicyclic Scaffold: Structure-based Design and Preparation of Conformationally Constrained Covalent and Non-Covalent Prolyl Oligopeptidase Inhibitors. J. Med. Chem. 2016, 59, 4221–4234.link

    13. Tomberg A., Pottel J., Liu Z., Labute P., Moitessier N. Understanding P450-mediated Bio-transformations into Epoxide and Phenolic Metabolites. Angew. Chem. Int. Ed. 2015, 54, 13743–13747. link

    14. Campagna-Slater V., Pottel J., Therrien E., Cantin L.-D., Moitessier N. Development of a computational tool to rival experts in the prediction of sites of metabolism of xenobiotics by P450s. J.Chem.Inf.Model. 2012, 52, 2471-2483. link