Towards the development of novel compounds integrating medicinal and computational chemistry

An In-depth look at our research projects

  • Developing drugs targeting SARS-CoV-2 to treat COVID-19
  • Targeting serine protases to treat cancer and neurodegenerative diseases
  • Targetting dipeptidyl peptidase 8/9 (DPP8/9) for cancer immunotherapy
  • Targeting activation-induced cytidinde deaminase (AID) for the treatment of leukemia
  • Fighting against metabolic drug resistance
  • Predicting sites of metabolism, reactive metabolite formation and CYP inhibition
  • Improving molecular mechanics using chemistry principlesand the H-TEQ method
  • Designing asymmetric catalysis with the Virtual Chemist platform
  • Accurately predicting the conformational preferences of nucleosides