Timeline

  1. Burai Patrascu, M.; Plescia, J.; Kalgutkar, A.; Mascitti. V.; Moitessier, N. Computational methods for prediction of drug properties – Application to metabolism prediction. ARKIVOC (Special issue in honor of Prof. Hanessian) 2019, 280-298. link

  2. Schiavini, P., Cheong K.J., Moitessier N., Auclair K. Active site crowding of P450 3A4 as a strategy to alter its selectivity. ChemBioChem 2017, 18, 248–252. link

  3. Tomberg A., Pottel J., Liu Z., Labute P., Moitessier N. Understanding P450-mediated Bio-transformations into Epoxide and Phenolic Metabolites. Angewandte Chemie International Edition 2015,54, 13743–13747. link

  4. Campagna-Slater V., Pottel J., Therrien E., Cantin L.-D., Moitessier N. Development of a computational tool to rival experts in the prediction of sites of metabolism of xenobiotics by P450s. Journal of Chemical Information and Modeling 2012, 52, 2471-2483 link

Back to publications