Timeline
- Mallet, V.; Oliver, C. G.; Moitessier, N. Waldispühl, J.* Leveraging binding-site structure for drug discovery with point-cloud methods. ARXIV 2019, preprint. link
- Oliver, C. G.; Mallet, V.; Sarrazin Gendron, R.; Reinharz, V.; Hamilton, W.L.; Moitessier, N.; Waldispühl, J.* Augmented base pairing networks encode RNA-small molecule binding preferences. Nucleic Acids Research 2019-2020 (preprint + full paper), ASAP. link
- Carlos G.; Oliver, C. G.; Sarrazin Gendron, R.; Moitessier, N.; Waldispuhl, J.* Automated, customizable and efficient identification of 3D base pair modules with Bayes Pairing. Nucleic Acids Research 2019, 47, 3321-3332. link
- Di Trani, J. M., Moitessier, N., Mittermaier A. K. Complete Kinetic Characterization of Enzyme Inhibition in a Single Isothermal Titration Calorimetric Experiment. Analytical Chemistry 2018, 90, 8430-8435. link
- Di Trani, J. M., De Cesco, S., O’Leary, R., Plescia, J., Jorge do Nascimento, C., Moitessier, N., Mittermaier, A. K. Rapid Measurement of Inhibitor Binding Kinetics by Isothermal Titration Calorimetry. Nature Communications 2018, 9, 893. link
- Tomberg, A.; Kundu, S., Zhou, F., Li, C.-J., Moitessier, N. Revised Mechanism for a Ruthenium-Catalyzed Coupling of Aldehyde and Terminal Alkyne. ACS-Omega 2018, 3, 3218–3227. link
- Di Trani J., Moitessier N., and Mittermaier A. Measuring Rapid Time-scale Reaction Kinetics Using Isothermal Titration Calorimetry. Analytical Chemistry 2017, 89, 7022–7030. link
- McCracken, A. N., McMonigle, R. J., Tessier, J., Fransson, R., Perryman, M. S., Chen, B., Keebaugh, A., Selwan, E., Barr, S. A., Kim, S. M., Roy, S. G., Liu, G., Fallegger, D., Sernissi, L., Brandt, C., Moitessier, N., Snider, A. J., Clare, S., Muschen, M., Huwiler, A., Kleinman, M. T., Hanessian, S., Edinger, A. L.Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. Leukemia 2017, 31, 669–677. link
- Bushuyev O. S., Tomberg A., Vinden J., Moitessier N., Barrett C.J., Friščić T. Azo···phenyl stacking: a persistent self-assembly motif guides the assembly of fluorinated cis-azobenzenes into photo-mechanical needle crystals. Chemical Communications 2016, 52, 2103-2106. link
- Mendoza-Sancheza R., Cotnoir-Whiteb D., Kulpab J., Jutrasb I., Pottel J., Moitessier N., Maderb S., Gleason J.L. Design, Synthesis and Evaluation of Antiestrogen and Histone Deacetylase Inhibitor Molecular Hybrids. Bioorganic & Medicinal Chemistry 2015, 23, 7597–7606. link
- Castor, K. J., Liu, Z., Fakhoury, J., Hancock, M. A., Mittermaier, A., Moitessier, N. and Sleiman, H. F. A Platinum(II) Phenylphenanthroimidazole with an Extended Side-Chain Exhibits Slow Dissociation from a c-Kit G-Quadruplex Motif. Chemistry - A European Journal 2013, 52, 17836–17845. link
- Castor K.J., Mancini J., Fakhoury J., Weill N., Kieltyka R., Englebienne P., Avakyan N., Mittermaier A., Autexier C., Moitessier N., Sleiman H.F., Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes. ChemMedChem 2012, 7, 85-94 link
- Kieltyka R., Englebienne P., Moitessier N., Sleiman H., Quantifying interactions between G-quadruplex DNA and transition-metal complexes. Methods in molecular biology (Clifton 2010, N.J.), 608, 223-255. link
- Kieltyka R., Englebienne P., Fakhoury J., Autexier C., Moitessier N., Sleiman H.F., A platinum supramolecular square as an effective G-quadruplex binder and telomerase inhibitor. Journal of the American Chemical Society 2008, 130, 10040-10041. link
- Kieltyka R., Fakhoury J., Moitessier N., Sleiman H.F., Platinum phenanthroimidazole complexes as G-quadruplex DNA selective binders. Chemistry - A European Journal 2008, 14, 1145-1154. link
- Moitessier N., Therrien E., Hanessian S., A method for induced-fit docking, scoring, and ranking of flexible ligands. Application to peptidic and pseudopeptidic β-secretase (BACE 1) inhibitors. Journal of Medicinal Chemistry 2006, 49, 5885-5894. link