Timeline

  1. Mallet, V.; Oliver, C. G.; Moitessier, N. Waldispühl, J.* Leveraging binding-site structure for drug discovery with point-cloud methods. ARXIV 2019, preprint. link

  2. Oliver, C. G.; Mallet, V.; Sarrazin Gendron, R.; Reinharz, V.; Hamilton, W.L.; Moitessier, N.; Waldispühl, J.* Augmented base pairing networks encode RNA-small molecule binding preferences. Nucleic Acids Research 2019-2020 (preprint + full paper), ASAP. link

  3. Carlos G.; Oliver, C. G.; Sarrazin Gendron, R.; Moitessier, N.; Waldispuhl, J.* Automated, customizable and efficient identification of 3D base pair modules with Bayes Pairing. Nucleic Acids Research 2019, 47, 3321-3332. link

  4. Di Trani, J. M., Moitessier, N., Mittermaier A. K. Complete Kinetic Characterization of Enzyme Inhibition in a Single Isothermal Titration Calorimetric Experiment. Analytical Chemistry 2018, 90, 8430-8435. link

  5. Di Trani, J. M., De Cesco, S., O’Leary, R., Plescia, J., Jorge do Nascimento, C., Moitessier, N., Mittermaier, A. K. Rapid Measurement of Inhibitor Binding Kinetics by Isothermal Titration Calorimetry. Nature Communications 2018, 9, 893. link

  6. Tomberg, A.; Kundu, S., Zhou, F., Li, C.-J., Moitessier, N. Revised Mechanism for a Ruthenium-Catalyzed Coupling of Aldehyde and Terminal Alkyne. ACS-Omega 2018, 3, 3218–3227. link

  7. Di Trani J., Moitessier N., and Mittermaier A. Measuring Rapid Time-scale Reaction Kinetics Using Isothermal Titration Calorimetry. Analytical Chemistry 2017, 89, 7022–7030. link

  8. McCracken, A. N., McMonigle, R. J., Tessier, J., Fransson, R., Perryman, M. S., Chen, B., Keebaugh, A., Selwan, E., Barr, S. A., Kim, S. M., Roy, S. G., Liu, G., Fallegger, D., Sernissi, L., Brandt, C., Moitessier, N., Snider, A. J., Clare, S., Muschen, M., Huwiler, A., Kleinman, M. T., Hanessian, S., Edinger, A. L.Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation. Leukemia 2017, 31, 669–677. link

  9. Bushuyev O. S., Tomberg A., Vinden J., Moitessier N., Barrett C.J., Friščić T. Azo···phenyl stacking: a persistent self-assembly motif guides the assembly of fluorinated cis-azobenzenes into photo-mechanical needle crystals. Chemical Communications 2016, 52, 2103-2106. link

  10. Mendoza-Sancheza R., Cotnoir-Whiteb D., Kulpab J., Jutrasb I., Pottel J., Moitessier N., Maderb S., Gleason J.L. Design, Synthesis and Evaluation of Antiestrogen and Histone Deacetylase Inhibitor Molecular Hybrids. Bioorganic & Medicinal Chemistry 2015, 23, 7597–7606. link

  11. Castor, K. J., Liu, Z., Fakhoury, J., Hancock, M. A., Mittermaier, A., Moitessier, N. and Sleiman, H. F. A Platinum(II) Phenylphenanthroimidazole with an Extended Side-Chain Exhibits Slow Dissociation from a c-Kit G-Quadruplex Motif. Chemistry - A European Journal 2013, 52, 17836–17845. link

  12. Castor K.J., Mancini J., Fakhoury J., Weill N., Kieltyka R., Englebienne P., Avakyan N., Mittermaier A., Autexier C., Moitessier N., Sleiman H.F., Platinum(II) phenanthroimidazoles for targeting telomeric G-quadruplexes. ChemMedChem 2012, 7, 85-94 link

  13. Kieltyka R., Englebienne P., Moitessier N., Sleiman H., Quantifying interactions between G-quadruplex DNA and transition-metal complexes. Methods in molecular biology (Clifton 2010, N.J.), 608, 223-255. link

  14. Kieltyka R., Englebienne P., Fakhoury J., Autexier C., Moitessier N., Sleiman H.F., A platinum supramolecular square as an effective G-quadruplex binder and telomerase inhibitor. Journal of the American Chemical Society 2008, 130, 10040-10041. link

  15. Kieltyka R., Fakhoury J., Moitessier N., Sleiman H.F., Platinum phenanthroimidazole complexes as G-quadruplex DNA selective binders. Chemistry - A European Journal 2008, 14, 1145-1154. link

  16. Moitessier N., Therrien E., Hanessian S., A method for induced-fit docking, scoring, and ranking of flexible ligands. Application to peptidic and pseudopeptidic β-secretase (BACE 1) inhibitors. Journal of Medicinal Chemistry 2006, 49, 5885-5894. link

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